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. 1990 May;37(2):206-9.
doi: 10.1016/0090-8258(90)90334-h.

Role of centralization of surgery in Stage IB carcinoma of the cervix: a review of 498 cases

J M Monaghan  1 , D Ireland, S Mor-Yosef, S E Pearson, A Lopes, D P Sinha
Affiliations

Role of centralization of surgery in Stage IB carcinoma of the cervix: a review of 498 cases

J M Monaghan et al. Gynecol Oncol. 1990 May.

Abstract

A review was undertaken of 498 patients with stage IB carcinoma of the cervix managed over a 15-year period in the Regional Gynaecological Oncology Centre, Gateshead. All but 4 were treated by radical hysterectomy, with adjuvant radiotherapy and/or chemotherapy for those with involved pelvic nodes. The overall 5-year survival in those with negative nodes was 91.4% compared with 50.5% in those with positive nodes (P less than 0.05). Of those dying from the disease, 7 patients only (1.4%) developed central recurrence, the remainder experiencing pelvic side-wall or distant recurrence. There was no difference in survival related to patient age. There were three deaths related to surgery and a fistula rate of only 1.2%. Bladder hypotonia and lymphocyst affected a minority of patients in the long term. The data support the case for radical surgery in stage IB carcinoma of the cervix, managed on a centralized referral basis.

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