Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012 Mar;7(1):23-9.
doi: 10.1007/s11552-012-9391-7. Epub 2012 Jan 19.

Surgical options for recalcitrant carpal tunnel syndrome with perineural fibrosis

Affiliations

Surgical options for recalcitrant carpal tunnel syndrome with perineural fibrosis

Joshua M Abzug et al. Hand (N Y). 2012 Mar.

Abstract

Surgical release of the transverse carpal ligament for the treatment of carpal tunnel syndrome (CTS) is, in general, a very successful procedure. Some patients, however, fail this standard release and have persistent or recurrent symptoms. Such recalcitrance may relate to incomplete release but more often relates to perineural or intraneural fibrosis of the median nerve. While there is no good treatment for intraneural fibrosis, numerous procedures have evolved in an attempt to treat perineural fibrosis which restricts nerve gliding. These include procedures to isolate the nerve from scar as well as procedures to bring neovascularization to the median nerve. This review describes the various surgical treatment options for recalcitrant CTS as well as their reported outcomes.

Keywords: Carpal tunnel release; Carpal tunnel syndrome; Recalcitrant carpal tunnel syndrome; Revision carpal tunnel.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
a Identification of a superficial vein in the forearm. b The vein has been split longitudinally and the intima portion has been placed against the median nerve. Subsequently, the vein was wrapped around the median nerve multiple times (courtesy of Shriners Hospital for Children, Philadelphia, PA)
Fig. 2
Fig. 2
Synthetic device placed around the median nerve (courtesy of Joshua Abzug, MD)
Fig. 3
Fig. 3
a Elevation of the hypothenar fat pad. b Placement of the hypothenar fat pad over the median nerve. (Courtesy of Shriners Hospital for Children, Philadelphia, PA)
Fig. 4
Fig. 4
a Elevation of the tenosynovial flap utilizing the ulnar aspect as the vascularized pedicle. b Placement of the vascularized tenosynovial flap over the median nerve (courtesy of The Philadelphia Hand Center, Philadelphia, PA)
Fig. 5
Fig. 5
a Elevation of the FDS muscle belly without disturbing the myotendinous junction. b Rotation of the vascularized FDS muscle belly 180° to cover the median nerve (courtesy of The Philadelphia Hand Center, Philadelphia, PA)

References

    1. Archibald SJ, Krarup C, Li ST, et al. A collagen-based nerve guide conduit for peripheral nerve repair: an electrophysiological study of nerve regeneration in rodents and nonhuman primates. J Comp Neurol. 1991;307:1–12. doi: 10.1002/cne.903070102. - DOI - PubMed
    1. Bikfalvi A, Alteiro J, Inyang AL, et al. Basic fibroblast growth factor expression in human omental microvascovascular endothelial cells and the effect of phorbol ester. J Cell Physiol. 1990;144:151–158. doi: 10.1002/jcp.1041440120. - DOI - PubMed
    1. Bloem JJ, Pradjarahardja MCL, Vuursteen PJ. The postcarpal tunnel syndrome. Causes and prevention. Neth J Surg. 1986;38:52–55. - PubMed
    1. Brunelli GA, Brunelli F, DiRosa F. Neurolized nerve padding in actinic lesions: omentum versus muscle use. An experimental study. Microsurgery. 1988;9:177–180. doi: 10.1002/micr.1920090303. - DOI - PubMed
    1. Cobb TK, Amadio PC, Leatherwood DF, et al. Outcome of reoperation for carpal tunnel syndrome. J Hand Surg. 1996;21A:347–356. - PubMed