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. 2013 May;93(2):77-9.
doi: 10.1016/j.mimet.2013.02.005. Epub 2013 Feb 28.

Time-to-positivity-based discrimination between Enterobacteriaceae, Pseudomonas aeruginosa and strictly anaerobic Gram-negative bacilli in aerobic and anaerobic blood culture vials

Gilles Defrance  1 , Gabriel Birgand, Etienne Ruppé, Morgane Billard, Raymond Ruimy, Christine Bonnal, Antoine Andremont, Laurence Armand-Lefèvre
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Time-to-positivity-based discrimination between Enterobacteriaceae, Pseudomonas aeruginosa and strictly anaerobic Gram-negative bacilli in aerobic and anaerobic blood culture vials

Gilles Defrance et al. J Microbiol Methods. 2013 May.

Abstract

Time-to-positivity (TTP) of first positive blood cultures growing Gram-negative bacilli (GNB) was investigated. When anaerobic vials were positive first, TTP ≤ 18 h differentiated Enterobacteriaceae from strict anaerobic Gram-negative bacilli (PPV 98.8%). When the aerobic ones were first, TTP ≤ 13 h differentiated Enterobacteriaceae from Pseudomonas aeruginosa and other GNB (PPV 80.8%).

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