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Comment
. 2013;18(3):242-4.
doi: 10.1634/theoncologist.2013-0014. Epub 2013 Mar 1.

Upholding the principles of autonomy, beneficence, and justice in phase I clinical trials

Affiliations
Comment

Upholding the principles of autonomy, beneficence, and justice in phase I clinical trials

Taofeek K Owonikoko. Oncologist. 2013.

Abstract

This commentary discusses the importance of maintaining the three core principles of autonomy, beneficence, and justice in phase I clinical trials.

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Conflict of interest statement

Disclosures of potential conflicts of interest may be found at the end of this article.

Comment on

References

    1. Kurzrock R, Stewart DJ. Compliance in early-phase cancer clinical trials research. The Oncologist. 2013;18:308–313. - PMC - PubMed
    1. Garcia VM, Cassier PA, de Bono J. Parallel anticancer drug development and molecular stratification to qualify predictive biomarkers: Dealing with obstacles hindering progress. Cancer Discov. 2011;1:207–212. - PubMed
    1. Fischer BA., 4th A summary of important documents in the field of research ethics. Schizophr Bull. 2006;32:69–80. - PMC - PubMed
    1. U.S Department of Health and Human Services. The Belmont Report: Ethical Principles and Guidelines for the Protection of Human Subjects of Research. [Accessed February 15, 2013]. Available at http://www.hhs.gov/ohrp/humansubjects/guidance/belmont.html.
    1. Horstmann E, McCabe MS, Grochow L, et al. Risks and benefits of phase 1 oncology trials, 1991 through 2002. N Engl J Med. 2005;352:895–904. - PubMed

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