Signaling by nuclear receptors
- PMID: 23457262
- PMCID: PMC3578364
- DOI: 10.1101/cshperspect.a016709
Signaling by nuclear receptors
Abstract
Nuclear receptors are activated by lipid-soluble signals (e.g., steroid hormones) that cross the plasma membrane. Once activated, most function as transcription factors to control gene expression for numerous biological processes.
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References
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- Berrabah W, Aumercier P, Lefebvre P, Staels B 2011. Control of nuclear receptor activities in metabolism by post-translational modifications. FEBS Lett 585: 1640–1650 - PubMed
-
- Boergesen M, Pedersen TA, Gross B, van Heeringen SJ, Hagenbeek D, Bindesboll C, Caron S, Lalloyer F, Steffensen KR, Nebb HI, et al. 2012. Genome-wide profiling of liver X receptor, retinoid X receptor, and peroxisome proliferator-activated receptor α in mouse liver reveals extensive sharing of binding sites. Mol Cell Biol 32: 852–867 - PMC - PubMed
-
- Carroll JS, Meyer CA, Song J, Li W, Geistlinger TR, Eeckhoute J, Brodsky AS, Keeton EK, Fertuck KC, Hall GF, et al. 2006. Genome-wide analysis of estrogen receptor binding sites. Nat Genet 38: 1289–1297 - PubMed
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