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. 2013 Mar;17(3):231-4.
doi: 10.1007/s12603-012-0383-7.

Hypovitaminosis D in psychogeriatric inpatients

M I Lapid  1 , M T Drake, J R Geske, C B Mundis, T L Hegard, S Kung, M A Frye
Affiliations

Hypovitaminosis D in psychogeriatric inpatients

M I Lapid et al. J Nutr Health Aging. 2013 Mar.

Abstract

Objectives: This study investigated the rate of hypovitaminosis D in psychogeriatric inpatients and explored whether any associations exist between vitamin D levels, cognitive function, and psychiatric diagnoses.

Design: Retrospective medical record review from November 2000 through November 2010.

Setting: Geriatric psychiatric ward of an academic tertiary care hospital.

Participants: Psychiatric inpatients aged 65 years or older. MEASUREMENTS AND ANALYSIS METHODS: Serum 25-hydroxyvitamin D [25(OH)D] levels were measured at admission. Associations between 25(OH)D levels, Mini-Mental State Examination (MMSE) scores were analyzed using Spearman correlations, and psychiatric diagnoses were analyzed using logistic regression models and Fisher's exact tests.

Results: In 141 subjects (mean age, 77.8 years; 86 [61%] female; 135 [96%] white), the most frequent diagnoses were major depressive disorder in 81 patients (57%), dementia in 38 (27%), delirium in 13 (9%), anxiety in 12 (8.5%), and bipolar disorder in 11 (8%). Mean MMSE score was 24±6.4 (range, 3-30). Forty-three subjects (30.4%) had mild to moderate vitamin D deficiency [25(OH)D, 10-24 ng/mL], and 6 (4.2%) had severe deficiency [25(OH)D <10 ng/mL].

Conclusions: Hypovitaminosis D was common in elderly psychiatric inpatients. No associations were found between vitamin D levels and global cognitive function or psychiatric diagnoses.

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