Strategic and operational aspects of a transfusion-free neonatal arterial switch operation
- PMID: 23460601
- PMCID: PMC3653451
- DOI: 10.1093/icvts/ivt010
Strategic and operational aspects of a transfusion-free neonatal arterial switch operation
Abstract
Blood transfusion-free complex congenital cardiac surgery in a neonate remains a challenge for multidisciplinary cardiac teams. At our institution, a 3.5 kg neonate, born to a family of Jehovah's Witnesses and postnatally diagnosed with dextro-transposition of the great arteries (d-TGA) and a small muscular ventricular septal defect, underwent a successful arterial switch operation without blood or platelet transfusion. Key points that contributed to success were optimal preoperative haematopoetic conditioning using erythropoietin and iron, a miniaturized cardiopulmonary bypass circuit including a low prime volume oxygenator and crystalloid cardioplegia, and a well-coordinated multidisciplinary team. We report an overview of the literature regarding blood transfusion-free complex congenital cardiac surgery.
Keywords: Arterial switch operation; Blood transfusion-free; Congenital cardiac surgery; Jehovah's Witness.
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