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Randomized Controlled Trial
. 2013 Oct;15(10):1655-62.
doi: 10.1093/ntr/ntt017. Epub 2013 Mar 4.

A randomized clinical trial of the efficacy of extended smoking cessation treatment for adolescent smokers

Steffani R Bailey  1 , Sarah A Hagen, Christina J Jeffery, Christopher T Harrison, Seth Ammerman, Susan W Bryson, Diana T Killen, Thomas N Robinson, Joel D Killen
Affiliations
Randomized Controlled Trial

A randomized clinical trial of the efficacy of extended smoking cessation treatment for adolescent smokers

Steffani R Bailey et al. Nicotine Tob Res. 2013 Oct.

Abstract

Introduction: Relatively few well-designed smoking cessation studies have been conducted with teen smokers. This study examined the efficacy of extended cognitive-behavioral treatment in promoting longer term smoking cessation among adolescents.

Methods: Open-label smoking cessation treatment consisted of 10 weeks of school-based, cognitive-behavioral group counseling along with 9 weeks of nicotine replacement (nicotine patch). A total of 141 adolescent smokers in continuation high schools in the San Francisco Bay Area were randomized to either 9 additional group sessions over a 14-week period (extended group) or 4 monthly smoking status calls (nonextended group). Intention-to-treat logistic regression analysis was used to assess the primary outcome of biologically confirmed (carbon monoxide < 9 ppm) point prevalence abstinence at Week 26 (6-month follow-up from baseline).

Results: At Week 26 follow-up, the extended treatment group had a significantly higher abstinence rate (21%) than the nonextended treatment (7%; OR = 4.24, 95% CI: 1.20-15.02). Females also were more likely to be abstinent at the follow-up than males (OR = 4.15, 95% CI: 1.17-14.71).

Conclusions: The significantly higher abstinence rate at follow-up for the extended treatment group provides strong support for continued development of longer term interventions for adolescent smoking cessation.

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Figures

Figure 1.
Figure 1.
Flowchart of attrition of adolescent smokers over 26 weeks.
See this image and copyright information in PMC

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