Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2013 Mar;20(3):274-81.
doi: 10.1038/nsmb.2518.

DNA methylation dynamics in health and disease

Yehudit Bergman  1 , Howard Cedar
Affiliations
Review

DNA methylation dynamics in health and disease

Yehudit Bergman et al. Nat Struct Mol Biol. 2013 Mar.

Erratum in

  • Nat Struct Mol Biol. 2013 Oct;20(10):1236

Abstract

DNA methylation is an epigenetic mark that is erased in the early embryo and then re-established at the time of implantation. In this Review, dynamics of DNA methylation during normal development in vivo are discussed, starting from fertilization through embryogenesis and postnatal growth, as well as abnormal methylation changes that occur in cancer.

PubMed Disclaimer

Comment in

  • The dynamic epigenome.
    [No authors listed] [No authors listed] Nat Struct Mol Biol. 2013 Mar;20(3):258. doi: 10.1038/nsmb.2534. Nat Struct Mol Biol. 2013. PMID: 23463309 No abstract available.

References

    1. Genome Res. 2010 Apr;20(4):434-9 - PubMed
    1. Cell Stem Cell. 2011 Feb 4;8(2):200-13 - PubMed
    1. Nat Cell Biol. 2008 Nov;10(11):1280-90 - PubMed
    1. Dev Cell. 2003 Apr;4(4):481-95 - PubMed
    1. Genes Dev. 2011 Dec 1;25(23):2436-52 - PubMed

Publication types

LinkOut - more resources