DNA methylation dynamics in health and disease
- PMID: 23463312
- DOI: 10.1038/nsmb.2518
DNA methylation dynamics in health and disease
Erratum in
- Nat Struct Mol Biol. 2013 Oct;20(10):1236
Abstract
DNA methylation is an epigenetic mark that is erased in the early embryo and then re-established at the time of implantation. In this Review, dynamics of DNA methylation during normal development in vivo are discussed, starting from fertilization through embryogenesis and postnatal growth, as well as abnormal methylation changes that occur in cancer.
Comment in
-
The dynamic epigenome.Nat Struct Mol Biol. 2013 Mar;20(3):258. doi: 10.1038/nsmb.2534. Nat Struct Mol Biol. 2013. PMID: 23463309 No abstract available.
Similar articles
-
Germline-derived DNA methylation and early embryo epigenetic reprogramming: The selected survival of imprints.Int J Biochem Cell Biol. 2015 Oct;67:128-38. doi: 10.1016/j.biocel.2015.04.014. Epub 2015 May 9. Int J Biochem Cell Biol. 2015. PMID: 25966912 Review.
-
Methylation dynamics during folliculogenesis and early embryo development in sheep.Reproduction. 2017 May;153(5):605-619. doi: 10.1530/REP-16-0644. Epub 2017 Mar 1. Reproduction. 2017. PMID: 28250235
-
Targets and dynamics of promoter DNA methylation during early mouse development.Nat Genet. 2010 Dec;42(12):1093-100. doi: 10.1038/ng.708. Epub 2010 Nov 7. Nat Genet. 2010. PMID: 21057502
-
Loss of methylation at H19 DMD is associated with biallelic expression and reduced development in cattle derived by somatic cell nuclear transfer.Biol Reprod. 2011 May;84(5):947-56. doi: 10.1095/biolreprod.110.087833. Epub 2011 Jan 19. Biol Reprod. 2011. PMID: 21248292 Free PMC article.
-
Insights into epigenetic patterns in mammalian early embryos.Protein Cell. 2021 Jan;12(1):7-28. doi: 10.1007/s13238-020-00757-z. Epub 2020 Jul 15. Protein Cell. 2021. PMID: 32671792 Free PMC article. Review.
Cited by
-
Epigenetic Contribution and Genomic Imprinting Dlk1-Dio3 miRNAs in Systemic Lupus Erythematosus.Genes (Basel). 2021 May 1;12(5):680. doi: 10.3390/genes12050680. Genes (Basel). 2021. PMID: 34062726 Free PMC article. Review.
-
Structural impact of complete CpG methylation within target DNA on specific complex formation of the inducible transcription factor Egr-1.FEBS Lett. 2015 Jul 8;589(15):1748-53. doi: 10.1016/j.febslet.2015.05.022. Epub 2015 May 19. FEBS Lett. 2015. PMID: 25999311 Free PMC article.
-
Epigenetic silencing of glutaminase 2 in human liver and colon cancers.BMC Cancer. 2013 Dec 14;13:601. doi: 10.1186/1471-2407-13-601. BMC Cancer. 2013. PMID: 24330717 Free PMC article.
-
An Epigenetic Role of Mitochondria in Cancer.Cells. 2022 Aug 13;11(16):2518. doi: 10.3390/cells11162518. Cells. 2022. PMID: 36010594 Free PMC article. Review.
-
Applications and potentials of nanopore sequencing in the (epi)genome and (epi)transcriptome era.Innovation (Camb). 2021 Aug 11;2(4):100153. doi: 10.1016/j.xinn.2021.100153. eCollection 2021 Nov 28. Innovation (Camb). 2021. PMID: 34901902 Free PMC article. Review.
References
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical