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. 1990 Apr;43(2):133-9.
doi: 10.1016/0885-4505(90)90018-v.

Targeting of urea stibamine encapsulated in liposomes to reticuloendothelial system for the treatment of experimental leishmaniasis

N Das  1 , S B Mahato, K Naskar, D K Ghosh, M K Basu
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Targeting of urea stibamine encapsulated in liposomes to reticuloendothelial system for the treatment of experimental leishmaniasis

N Das et al. Biochem Med Metab Biol. 1990 Apr.

Abstract

The antileishmanial antimonial drug urea stibamine was encapsulated in mannosylated and nonmannosylated liposomes and was tested against experimental leishmanial infection in hamsters. The study demonstrated that liposome encapsulation of urea stibamine enhanced its effectiveness, an effect which was greater when mannosylated liposomes were used.

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