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. 1990 Mar;38(3):698-700.
doi: 10.1248/cpb.38.698.

Studies on cytotoxic constituents in pericarps of Mallotus japonicus. IV

M Arisawa  1 , A Fujita, T Hayashi, N Morita, T Kikuchi, Y Tezuka
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Free article

Studies on cytotoxic constituents in pericarps of Mallotus japonicus. IV

M Arisawa et al. Chem Pharm Bull (Tokyo). 1990 Mar.
Free article

Abstract

Two new phloroglucinol derivatives, isomallotolerin (1) and isomallotochromanol (2), were isolated from the cytotoxic fraction of the pericarps of Mallotus japonicus. The new derivatives were identified as 3-(3-methyl-2-hydroxybut-3-enyl)-5-(3-acetyl-2,4-dihydroxy-5-methy l-6- methoxybenzyl)-phlorisobutyrophenone (1) and 6-acetyl-5,7-dihydroxy-8-(3-acetyl-2,4-dihydroxy-5-methyl-6-methoxybenzy l)-2,2- dimethyl-3-hydroxychroman (2) from chemical and spectral data. Isomallotolerin and its acetate were found to be cytotoxic to KB cell line.

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