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Comment
. 2013 Apr;54(4):878-80.
doi: 10.1194/jlr.E037572. Epub 2013 Mar 7.

ApoA-I mimetics: tomatoes to the rescue

Godfrey S Getz  1 , Catherine A Reardon
Affiliations
Comment

ApoA-I mimetics: tomatoes to the rescue

Godfrey S Getz et al. J Lipid Res. 2013 Apr.
No abstract available

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Figures

Fig. 1.
Fig. 1.
The reduction in the oxidative intermediates in the intestine mediated by the apoA-I mimetic peptides may lead to decreased levels of circulating proinflammatory oxidative intermediates resulting in decreased proinflammatory responses in the arterial vessel wall and other tissue such as the liver.
See this image and copyright information in PMC

Comment on

  • A novel approach to oral apoA-I mimetic therapy.
    Chattopadhyay A, Navab M, Hough G, Gao F, Meriwether D, Grijalva V, Springstead JR, Palgnachari MN, Namiri-Kalantari R, Su F, Van Lenten BJ, Wagner AC, Anantharamaiah GM, Farias-Eisner R, Reddy ST, Fogelman AM. Chattopadhyay A, et al. J Lipid Res. 2013 Apr;54(4):995-1010. doi: 10.1194/jlr.M033555. Epub 2013 Feb 2. J Lipid Res. 2013. PMID: 23378594 Free PMC article.

References

    1. Chattopadhyay A., Navab M., Hough G., Gao G., Meriwether D., Grijalva V., Springstead J. R., Palgnachari M. N., Namiri-Kalantari R., Su F., et al. 2013. A novel approach to oral apoA-I mimetic therapy. J. Lipid Res. 54: 995–1010. - PMC - PubMed
    1. Van Lenten B. J., Navab M., Anantharamaiah G. M., Buga G. M., Reddy S. T., Fogelman A. M. 2008. Multiple indications for anti-inflammatory apolipoproteins mimetic peptides. Curr. Opin. Investig. Drugs. 9: 1157–1162. - PMC - PubMed
    1. Getz G. S., Reardon C. A. 2011. Apolipoprotein A-I and A-I mimetic peptides: a role in atherosclerosis. J Inflamm. Res. 4: 83–92. - PMC - PubMed
    1. Anantharamaiah G. M., Jones J. L., Brouillette C. G., Schmidt C. F., Chung B. H., Hughes T. A., Bhown A. S., Segrest J. P. 1985. Studies of synthetic peptide analogs of the amphipathic helix. Structure of complexes with dimyristoyl phosphatidycholine. J. Biol. Chem. 260: 10248–10255. - PubMed
    1. Datta G., Chaddha M., Hama S., Navab M., Fogelman A. M., Garber D. W., Mishra V. K., Epand R. M., Epand R. F., Lund-Katz S., et al. 2001. Effects of increasing hydrophobicity on the physical-chemical and biological properties of a class A amphipathic helical peptide. J. Lipid Res. 42: 1096–1104. - PubMed

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