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. 2013 Apr 22;19(17):5242-5.
doi: 10.1002/chem.201204305. Epub 2013 Mar 7.

Synthesis of indolizines and heterocyclic chalcones catalyzed by supported copper nanoparticles

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Synthesis of indolizines and heterocyclic chalcones catalyzed by supported copper nanoparticles

María José Albaladejo et al. Chemistry. .

Abstract

Solvent decides: Versatile copper nanoparticles (Cu NPs) on activated carbon have been found to catalyze the multicomponent synthesis of indolizines in dichloromethane and the synthesis of heterocyclic chalcones in the absence of solvent, in both cases, from pyridine-2-carbaldehyde derivatives, secondary amines, and terminal alkynes (see scheme).

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