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Comment
. 2013 Mar 5;17(3):315-7.
doi: 10.1016/j.cmet.2013.02.015.

A new "immunological" role for adipocytes in obesity

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A new "immunological" role for adipocytes in obesity

Zuzana Hruskova et al. Cell Metab. .
Free article

Abstract

Obesity-induced insulin resistance is associated with low-grade adipose tissue inflammation, but the mechanism driving this process remains unclear. In this issue of Cell Metabolism, a study by Deng et al. (2013) demonstrates a direct immunological role of adipocytes in instigating adipose inflammation via a MHCII-dependent process.

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