A new "immunological" role for adipocytes in obesity
- PMID: 23473027
- DOI: 10.1016/j.cmet.2013.02.015
A new "immunological" role for adipocytes in obesity
Abstract
Obesity-induced insulin resistance is associated with low-grade adipose tissue inflammation, but the mechanism driving this process remains unclear. In this issue of Cell Metabolism, a study by Deng et al. (2013) demonstrates a direct immunological role of adipocytes in instigating adipose inflammation via a MHCII-dependent process.
Copyright © 2013 Elsevier Inc. All rights reserved.
Comment on
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Class II major histocompatibility complex plays an essential role in obesity-induced adipose inflammation.Cell Metab. 2013 Mar 5;17(3):411-22. doi: 10.1016/j.cmet.2013.02.009. Cell Metab. 2013. PMID: 23473035 Free PMC article.
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