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Comment
. 2013 Mar 5;17(3):317-8.
doi: 10.1016/j.cmet.2013.02.013.

Xenobiotics and the human gut microbiome: metatranscriptomics reveal the active players

Luke K Ursell  1 , Rob Knight
Affiliations
Comment

Xenobiotics and the human gut microbiome: metatranscriptomics reveal the active players

Luke K Ursell et al. Cell Metab. .

Abstract

The human gut microbiome plays an important role in the metabolism of xenobiotics. In a recent issue of Cell, Maurice et al. (2013) identify the active members of the gut microbiome and show how gene-expression profiles change within the gut microbial community in response to antibiotics and host-targeted xenobiotics.

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References

    1. Blaut M. Ecology and Physiology of the Intestinal Tract. Curr Top Microbiol Immunol 2011 - PubMed
    1. Caporaso JG, Lauber CL, Costello EK, Berg-Lyons D, Gonzalez A, Stombaugh J, Knights D, Gajer P, Ravel J, Fierer N, et al. Moving pictures of the human microbiome. Genome Biol. 2011;12:R50. - PMC - PubMed
    1. Clayton TA, Baker D, Lindon JC, Everett JR, Nicholson JK. Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism. Proceedings of the National Academy of Sciences of the United States of America. 2009;106:14728–14733. - PMC - PubMed
    1. Clemente JC, Ursell LK, Parfrey LW, Knight R. The impact of the gut microbiota on human health: an integrative view. Cell. 2012;148:1258–1270. - PMC - PubMed
    1. Dethlefsen L, Relman DA. Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation. Proceedings of the National Academy of Sciences of the United States of America. 2011;108(Suppl 1):4554–4561. - PMC - PubMed