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Comment
. 2013 Mar 5;21(3):315-6.
doi: 10.1016/j.str.2013.02.009.

MultIDIMensionality of IDIMs: intrinsic disorder in autoinhibition

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MultIDIMensionality of IDIMs: intrinsic disorder in autoinhibition

Vladimir N Uversky. Structure. .
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Abstract

Intrinsic disorder (ID) is crucial for the function of many proteins. The activity of some proteins is autoinhibited by their inhibitory modules (IMs). In this issue of Structure, Trudeau and colleagues showed multifarious roles of ID in controlling agility of IMs.

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