2-[4-(Morpholin-4-ylmeth-yl)phen-yl]benzonitrile
- PMID: 23476389
- PMCID: PMC3588350
- DOI: 10.1107/S1600536812050957
2-[4-(Morpholin-4-ylmeth-yl)phen-yl]benzonitrile
Abstract
In the title compound, C18H18N2O, the morpholine ring adopts a chair conformation with the exocyclic N-C bond in an equatorial orientation. The dihedral angles between the central benzene ring and the morpholine ring (all atoms) and the cyano-benzene ring are 87.87 (7) and 52.54 (7)°, respectively. No significant inter-molecular inter-actions are observed in the crystal structure.
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References
-
- Bruker (2001). SMART and SAINT. Bruker AXS Inc., Madison, Wisconsin, USA.
-
- Chan, W., Butler, R. G. & Smith, R. G. (1994). J. Med. Chem. 37, 897–906. - PubMed
-
- Farrugia, L. J. (2012). J. Appl. Cryst. 45, 849–854.
-
- Hadizad, T., Kirkpatrick, A. S., Mason, S., Burns, K., Beanlands, R. S. & Dasilva, J. N. (2009). Bioorg. Med. Chem. 23, 7971–7977. - PubMed
-
- Kamble, R. R., Biradar, D. B., Meti, G. Y., Tasneem, T., Tegginamath, G., Khazi, I. M., Vaidynathan, S. T., Mohandoss, R. & Balasubramanian, S. V. P. (2011). J. Chem. Sci. 123, 393–401.
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