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. 2013:2013:956149.
doi: 10.1155/2013/956149. Epub 2013 Feb 14.

Epidemiology of Acute Pancreatitis in the North Adriatic Region of Croatia during the Last Ten Years

Davor Stimac  1 , Ivana Mikolasevic, Irena Krznaric-Zrnic, Mladen Radic, Sandra Milic
Affiliations

Epidemiology of Acute Pancreatitis in the North Adriatic Region of Croatia during the Last Ten Years

Davor Stimac et al. Gastroenterol Res Pract. 2013.

Abstract

Introduction. Several European studies have reported an increase in the incidence rate of acute pancreatitis (AP). Therefore, we studied the incidence rate of AP in the North Adriatic Region in Croatia, as well as epidemiological analysis concerning etiology, age, gender, and severity of disease. Methods. We analyzed 922 patients with confirmed diagnosis of AP (history, clinical and laboratory findings, and imaging methods) admitted to our hospital during a ten-year period (2000-2009). Epidemiological analysis was carried out focusing on incidence, demographic data, and etiology, as well as severity of the disease based on the Ranson and APACHE II scores. Results. The incidence rate varied from 24 to 35/100 000 inhabitants annually. Mean age was 60 ± 16 years. There were 53% men and 47% women among the patients. Most frequent etiologies of AP were biliary stones in 60% and alcohol abuse in 19% of patients. According to the Ranson and APACHE II scores, pancreatitis was considered to be severe in 50% and 43% of the cases, respectively. Conclusion. In our region the incidence of AP was around 30 per 100,000 population per year during the ten-year period studied. The mean age at admission was 60 years and etiology was predominantly biliary. In our region, we have shown epidemiological characteristics of AP typical for Mediterranean countries.

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Figures

Figure 1
Figure 1
The incidence of acute pancreatitis according to gender during the ten-year period.
Figure 2
Figure 2
The incidence and etiology of acute pancreatitis change with aging. (M: male; F: female; T: total).
Figure 3
Figure 3
(a) The commonest causes of AP in men (HyperTG: hypertriglyceridemia). (b) The commonest causes of AP in female patients. One should note the rather low proportion of alcoholic AP as opposed to men (HyperTG: hypertriglyceridemia). (c) The commonest causes of AP in all patients (HyperTG: hypertriglyceridemia).
Figure 4
Figure 4
The distribution of the commonest etiologies of acute pancreatitis in the observed period.
See this image and copyright information in PMC

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