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. 2011 Dec;4(4):137-40.
doi: 10.1007/s12177-012-9077-y. Epub 2012 Mar 8.

Alterations in "in vivo" histology of retina in bilateral chronic central serous chorioretinopathy after intravitreal bevacizumab

Sandeep Saxena  1 , Astha Jain
Affiliations

Alterations in "in vivo" histology of retina in bilateral chronic central serous chorioretinopathy after intravitreal bevacizumab

Sandeep Saxena et al. J Ocul Biol Dis Infor. 2011 Dec.
No abstract available

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Figures

Fig. 1
Fig. 1
a Color fundus photograph of the right eye shows retinal pigment epithelium atrophy, few superficial and deep hemorrhages and hard exudates at the posterior pole. b Color fundus photograph of the left eye shows retinal pigment epithelium atrophy tract, few superficial and deep hemorrhages, and hard exudates at the posterior pole
Fig. 2
Fig. 2
a Spectral domain optical coherence tomography of the right eye shows neurosensory detachment of the macula with retinal pigment epithelial detachment. Granularity in the outer photoreceptor layer and proliferative retinal pigment epithelial cells are also observed. The retinal pigment epithelium is hyperplastic. The photoreceptor IS–OS junction is not visualized. b Spectral domain optical coherence tomography of the left eye shows neurosensory detachment of the macula with retinal pigment epithelial detachment. Granularity in the outer photoreceptor layer and proliferative retinal pigment epithelial cells are also observed. The retinal pigment epithelium is hyperplastic. The photoreceptor IS–OS junction is not visualized
Fig. 3
Fig. 3
a Three-dimensional internal limiting membrane-retinal pigment epithelium map of the right eye shows increased macular thickness. Central sub field thickness is 444 μm. b Three-dimensional internal limiting membrane-retinal pigment epithelium map of the left eye shows increased macular thickness. Central sub field thickness was 324 μm
Fig. 4
Fig. 4
a Post intravitreal bevacizumab injection, spectral domain optical coherence tomography of the right eye shows resolution of subretinal fluid with persistent pigment epithelial detachment. Foveal contour is restored. Residual granularity at outer photoreceptor layer and proliferative retinal pigment epithelial cells are visualized. Small cystic spaces are also observed. The photoreceptor IS–OS junction is not visible in the subfoveal area. The retinal pigment epithelium layer remains hyperplastic. b Three-dimensional internal limiting membrane-retinal pigment epithelium map of the right eye shows decreased macular thickness. Central subfield thickness is 216 μm
Fig. 5
Fig. 5
a Post intravitreal bevacizumab injection, spectral domain optical coherence tomography of the left eye shows resolution of subretinal fluid. Foveal contour is restored. Residual granularity at outer photoreceptor layer and proliferative retinal pigment epithelial cells are visualized. The photoreceptor IS–OS junction is visualized in the subfoveal area. b Three-dimensional internal limiting membrane-retinal pigment epithelium map of the left eye shows decreased macular thickness. Central subfield thickness is 238 μm
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