Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2013 Apr;17(2):71-84.
doi: 10.1007/s40291-013-0023-x.

Bladder cancer detection and monitoring: assessment of urine- and blood-based marker tests

Affiliations
Review

Bladder cancer detection and monitoring: assessment of urine- and blood-based marker tests

Steve Goodison et al. Mol Diagn Ther. 2013 Apr.

Abstract

Bladder cancer is one of the most prevalent cancers worldwide, but the treatment and management of this disease can be very successful if the disease is detected early. The development of molecular assays that could diagnose bladder cancer accurately, and at an early stage, would be a significant advance. Ideally, such molecular assays would be applicable to non-invasively obtained body fluids, and be designed not only for diagnosis but also for monitoring disease recurrence and response to treatment. In this article, we assess the performance of current diagnostic assays for bladder cancer and discuss some of the emerging biomarkers that could be developed to augment current bladder cancer detection strategies.

PubMed Disclaimer

References

    1. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2012. CA Cancer J Clin. 2012;62(1):10–29. doi: 10.3322/caac.20138. - DOI - PubMed
    1. Kaufman DS, Shipley WU, Feldman AS. Bladder cancer. Lancet. 2009;374(9685):239–249. doi: 10.1016/S0140-6736(09)60491-8. - DOI - PubMed
    1. Millan-Rodriguez F, Chechile-Toniolo G, Salvador-Bayarri J, Palou J, Algaba F, Vicente-Rodriguez J. Primary superficial bladder cancer risk groups according to progression, mortality and recurrence. J Urol. 2000;164(3 Pt 1):680–684. doi: 10.1016/S0022-5347(05)67280-1. - DOI - PubMed
    1. Trivedi D, Messing EM. Commentary: the role of cytologic analysis of voided urine in the work-up of asymptomatic microhematuria. BMC Urol. 2009;9:13. doi: 10.1186/1471-2490-9-13. - DOI - PMC - PubMed
    1. Tetu B. Diagnosis of urothelial carcinoma from urine. Mod Pathol. 2009;22(Suppl 2):S53–S59. doi: 10.1038/modpathol.2008.193. - DOI - PubMed

Publication types

MeSH terms

Substances