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Randomized Controlled Trial
. 2013;32(1):46-52.
doi: 10.1080/10550887.2012.759870.

Symptoms of depression and smoking behaviors following treatment with transdermal nicotine patch

Robert A Schnoll  1 , Frank T Leone, Brian Hitsman
Affiliations
Randomized Controlled Trial

Symptoms of depression and smoking behaviors following treatment with transdermal nicotine patch

Robert A Schnoll et al. J Addict Dis. 2013.

Abstract

Subscales from the Center for Epidemiologic Studies depression scale (CESD), assessed prior to treatment, were examined as predictors of withdrawal, craving, and affect during the first week of abstinence, as well as smoking abstinence during the first week of abstinence and at the end of treatment. The negative affect and somatic features CESD subscales were related to higher levels of nicotine withdrawal. The relationship between the interpersonal disturbance CESD subscale and nicotine withdrawal approached significance. This study suggests the need to examine novel psychological mechanisms that may account for the relationship between depression symptoms and smoking cessation.

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Conflict of interest statement

DECLARATION OF CONFLICTING INTERESTS

Dr. Schnoll has served as a consultant to GlaxoSmithKline, the company that manufactures the nicotine patch used in this study. However, GSK did not provide medication or financial support for this study.

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