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. 2013 Mar;10(1):92-4.
doi: 10.4306/pi.2013.10.1.92. Epub 2013 Feb 8.

A case of clozapine induced acute renal failure

Na Young An  1 , Jeewon Lee, Jai Sung Noh
Affiliations

A case of clozapine induced acute renal failure

Na Young An et al. Psychiatry Investig. 2013 Mar.

Abstract

There have been a few case reports that clozapine, an atypical antipsychotic, caused acute renal failure of interstitial type. Here we report a case of a 38-year-old Korean male patient with treatment-resistant bipolar I disorder who developed acute renal failure after the initiation of treatment with clozapine. We describe the clinical and laboratory findings of the case and discuss the measures for early detection of this life threating condition. Within our knowledge, this is the first report of clozapine-induced acute renal failure in South Korea.

Keywords: Acute renal failure; Bipolar I disorder; Clozapine; Interstitial nephritis.

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