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Case Reports
. 2013 Oct;30(7):674-6.
doi: 10.3109/08880018.2013.775616. Epub 2013 Mar 13.

Voriconazole induced bradycardia

Dilek Uludağ  1 , Nihal Ozdemir, Gülen Tüysüz, Ayşe Güler Eroğlu, Tiraje Celkan
Affiliations
Case Reports

Voriconazole induced bradycardia

Dilek Uludağ et al. Pediatr Hematol Oncol. 2013 Oct.

Abstract

Voriconazole is a triazole antifungal drug that is used to treat invasive fungal infections, especially aspergillus. Here, we report two children who had severe bradycardia associated with voriconazole at a dose of 12 mg/kg per day. Bradycardia resolved in 24 hours in both after decreasing the dose to 10 mg/kg per day. Heart rates were in normal limits on follow-up. Bradycardia may be a side effect of voriconazole treatment in children under immunosuppressive treatment. Heart rate should be monitored in patients receiving voriconazole and other triazole treatments.

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