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Review
. 2013 Mar;95(2):e38-40.
doi: 10.1308/003588413X13511609955931.

Neurofibroma of the bile duct: a rare cause of obstructive jaundice

A De Rosa  1 , D Gomez, A M Zaitoun, I C Cameron
Affiliations
Review

Neurofibroma of the bile duct: a rare cause of obstructive jaundice

A De Rosa et al. Ann R Coll Surg Engl. 2013 Mar.

Abstract

Neurofibromas of the common bile duct are extremely rare. The lack of specific clinical or radiological features makes preoperative diagnosis in the absence of histology difficult. We report the case of a female patient who presented with obstructive jaundice and evidence of a common bile duct stricture on imaging. She underwent an exploratory laparotomy, and intraoperative frozen section confirmed clear margins and a benign lesion. Excision of the extrahepatic bile duct and A Rouxen-Y hepaticojejunostomy was performed. We discuss the clinical features and management of neurofibromas of the bile duct in light of the literature.

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Figures

Figure 1
Figure 1
Coronal section of contrast-enhanced computed tomography of the abdomen and pelvis demonstrating a stricture at the mid-common bile duct (arrow)
Figure 2
Figure 2
Haematoxylin and eosin stained section of the bile duct wall showing spindle cell proliferation (4× magnification)
Figure 3
Figure 3
Positive staining of the lesion with S100, a marker for neurofilament protein (10× magnification)
See this image and copyright information in PMC

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