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. 1990 May 25;18(10):2855-9.
doi: 10.1093/nar/18.10.2855.

Abasic oligodeoxyribonucleoside phosphorothioates: synthesis and evaluation as anti-HIV-1 agents

R P Iyer  1 , B Uznanski, J Boal, C Storm, W Egan, M Matsukura, S Broder, G Zon, A Wilk, M Koziolkiewicz, et al.
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Free PMC article

Abasic oligodeoxyribonucleoside phosphorothioates: synthesis and evaluation as anti-HIV-1 agents

R P Iyer et al. Nucleic Acids Res. .
Free PMC article

Abstract

The syntheses and anti-HIV-1 evaluations of two, abasic oligodeoxyribonucleotide phosphorothioate analogs, d[Cps(Eps)26C] and d[Cps(Vps)26C] (where E and V derive from 1,2-dideoxy-D-ribofuranose and (+/-)-butane 1, 3-diol, respectively), are described.

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References

    1. Nucleic Acids Res. 1984 Oct 11;12(19):7435-53 - PubMed
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    1. J Biol Chem. 1987 Jul 25;262(21):10171-9 - PubMed
    1. Proc Natl Acad Sci U S A. 1987 Nov;84(21):7706-10 - PubMed
    1. Proc Natl Acad Sci U S A. 1988 Oct;85(19):7079-83 - PubMed

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