Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Controlled Clinical Trial
. 2013 May;28(3):284-8.
doi: 10.1177/1533317513481090. Epub 2013 Mar 14.

Utility of the AD8 as a self-rating tool for cognitive impairment in an Asian population

Rowena Chin  1 , Amanda Ng, Kaavya Narasimhalu, Nagaendran Kandiah
Affiliations
Controlled Clinical Trial

Utility of the AD8 as a self-rating tool for cognitive impairment in an Asian population

Rowena Chin et al. Am J Alzheimers Dis Other Demen. 2013 May.

Abstract

Background: AD8 is a brief informant interview used to detect early cognitive change. This study evaluated the diagnostic performance of the participant-rated AD8 (p-AD8) in a predominantly Chinese population.

Methods: Data on demographics, clinical, and cognitive features were collected from 73 participants with no cognitive impairment (NCI), 27 participants with mild cognitive impairments, and 78 participants with Alzheimer's disease-informant dyads. Agreement and discriminative properties of p-AD8 were assessed.

Results: AD8 scores were associated with dementia severity. Participant and informant AD8 scores were moderately correlated within dementia dyads. The p-AD8 showed good diagnostic performance in differentiating between participants with NCI and participants with cognitive impairment (sensitivity = 85.0%, specificity = 74.0%, and area under the curve = 0.80), with a cutoff score of ≥1. Combination of impairment in Mini-Mental State Examination and p-AD8 is more useful in detecting cognitive impairment than using the AD8 alone.

Conclusion: Within a transcultural setting, the p-AD8 demonstrated good discriminative validity and can be used to gain a preliminary understanding of an individual's cognitive status.

PubMed Disclaimer

Conflict of interest statement

The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

References

    1. Brookmeyer R, Johnson E, Ziegler-Graham K, Arrighi HM. Forecasting the global burden of Alzheimer's disease. Alzheimers Dement. 2007;3(3):186–191. - PubMed
    1. Folstein MF, Folstein SE, McHugh PR. Mini-Mental State: a practical method for grading the cognitive state of patients for the clinicians. J Psychiatr Res. 1975;12(3):189–198. - PubMed
    1. Lawrence J, Davidoff D, Katt-Lloyd D, Auerbach M, Hennen J. A pilot program of improved methods for community-based screening for dementia. Am J Geriatr Psychiatry. 2001;9(3):205–211. - PubMed
    1. Lorentz W, Scanlan J, Borson S. Brief screening tests for dementia. Can J Psychiatry. 2002;47(8):723–733. - PubMed
    1. Smith T, Gildeh N, Holmes C. The Montreal cognitive assessment: validity and utility in a memory clinic setting. Can J Psychiatry. 2007;52(5):329–332. - PubMed

Publication types

MeSH terms