Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Multicenter Study
. 2013 Mar 15:6:19570.
doi: 10.3402/gha.v6i0.19570.

Determinants of antiretroviral treatment adherence among HIV/AIDS patients: a multisite study

Bach Xuan Tran  1 , Long Thanh Nguyen, Nga Hoang Nguyen, Quynh Van Hoang, Jongnam Hwang
Affiliations
Multicenter Study

Determinants of antiretroviral treatment adherence among HIV/AIDS patients: a multisite study

Bach Xuan Tran et al. Glob Health Action. .

Abstract

Introduction: Adherence to antiretroviral treatment (ART) is vital in achieving virological treatment success. This study assessed the prevalence of optimal ART adherence and its determinants among HIV/AIDS patients in Vietnam.

Method: A cross-sectional survey was conducted with 1,016 HIV/AIDS patients at seven hospitals and health centers providing antiretroviral treatment services in three provinces, including Hanoi, Hai Phong, and Ho Chi Minh City. Self-reported medication adherence was measured using a 30-day visual analog scale (VAS) and 7-day missed-doses questions.

Results: The mean adherence VAS-score was 94.5 out of 100 (SD=8.2), ranging from 40 to 100%. The rate of suboptimal adherence was 25.9%. The rate of missed-doses was 25.2%. In multivariate analysis, increased perceived self-efficacy, use of mobile phone alarms, and reminders from family members were associated with optimal adherence; higher CD4 level, single status, and unstable employment were associated with suboptimal adherence.

Conclusion: High rate of suboptimal adherence observed in this study highlights the importance of adherence support interventions during ART. The use of mobile phone reminders, involvement of relatives, and HIV self-management training programs have the potential to improve ART adherence in Vietnam.

Keywords: HIV/AIDS; Vietnam; adherence; adherence aid; antiretroviral treatment; drug users.

PubMed Disclaimer

References

    1. WHO. Antiretroviral therapy for HIV infection in adults and adolescents: recommendations for a public health approach, 2006 revision; Geneva: World Health Organization; 2006. - PubMed
    1. WHO. Geneva: World Health Organization; 2009. Rapid advice: antiretroviral therapy for HIV infection in adults and adolescents. - PubMed
    1. Tran BX, Nguyen N, Ohinmaa A, Duong AT, Nguyen LT, Van Hoang M, et al. Prevalence and correlates of alcohol use disorders during antiretroviral treatment in injection-driven HIV epidemics in Vietnam. Drug Alcohol Depend. 2012;127:39–44. - PubMed
    1. Tran BX, Ohinmaa A, Nguyen LT, Nguyen TA, Nguyen TH. Determinants of health-related quality of life in adults living with HIV in Vietnam. AIDS Care. 2011;23:1236–45. - PubMed
    1. Tran BX. Quality of life outcomes of antiretroviral treatment for HIV/AIDS patients in Vietnam. PLoS One. 2012;7:e41062. - PMC - PubMed

Publication types

Substances