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Review
. 2013 Dec;31(8):1826-45.
doi: 10.1016/j.biotechadv.2013.02.006. Epub 2013 Mar 14.

Recent advances in marine drug research

Saradavey Vinothkumar  1 , P S Parameswaran
Affiliations
Review

Recent advances in marine drug research

Saradavey Vinothkumar et al. Biotechnol Adv. 2013 Dec.

Abstract

Structures and properties of promising marine anti-cancer, anti-inflammation and anti-infectious (HIV, HSV, malaria, leishmania) compounds reported during 2008-2011 are discussed. Wherever possible, attempts have also been made to highlight their possible biogenesis or structure-activity relationships (SAR). Since the stress is on identifying and short-listing potential drug molecules, this review is restricted to only those compounds exhibiting promising in vitro activity, the arbitrary cut off being IC50<15 μM, reported during the above period.

Keywords: Alkaloid; Anti-cancer; Anti-infectious; Anti-inflammation; Depsipeptide; Lipopeptide; Sponge.

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