Comment on

• Th17/Treg imbalance in murine cystic fibrosis is linked to indoleamine 2,3-dioxygenase deficiency but corrected by kynurenines.

  Iannitti RG, Carvalho A, Cunha C, De Luca A, Giovannini G, Casagrande A, Zelante T, Vacca C, Fallarino F, Puccetti P, Massi-Benedetti C, Defilippi G, Russo M, Porcaro L, Colombo C, Ratclif L, De Benedictis FM, Romani L. Iannitti RG, et al. Am J Respir Crit Care Med. 2013 Mar 15;187(6):609-20. doi: 10.1164/rccm.201207-1346OC. Epub 2013 Jan 10. Am J Respir Crit Care Med. 2013. PMID: 23306541
• A Th17- and Th2-skewed cytokine profile in cystic fibrosis lungs represents a potential risk factor for Pseudomonas aeruginosa infection.

  Tiringer K, Treis A, Fucik P, Gona M, Gruber S, Renner S, Dehlink E, Nachbaur E, Horak F, Jaksch P, Döring G, Crameri R, Jung A, Rochat MK, Hörmann M, Spittler A, Klepetko W, Akdis CA, Szépfalusi Z, Frischer T, Eiwegger T. Tiringer K, et al. Am J Respir Crit Care Med. 2013 Mar 15;187(6):621-9. doi: 10.1164/rccm.201206-1150OC. Epub 2013 Jan 10. Am J Respir Crit Care Med. 2013. PMID: 23306544