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Review
. 2013 Mar 19;17(2):218.
doi: 10.1186/cc12527.

Point-of-care coagulation management in intensive care medicine

Patrick Meybohm, Kai Zacharowski, Christian F Weber
Review

Point-of-care coagulation management in intensive care medicine

Patrick Meybohm et al. Crit Care. .
No abstract available

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Figures

Figure 1
Figure 1
Overview of coagulopathies typically present in critically ill patients. DIC: disseminated intravascular coagulopathy; HIT: heparin-induced thrombocytopenia.
Figure 2
Figure 2
Primary and secondary outcomes of the first prospective randomized study in complex cardiac surgery including viscoelastic and aggregometric measures into a point-of-care (POC)-based algorithm for hemotherapy as proof-of-concept [13]. (a) Packed red blood cells (PRBC), fresh frozen plasma (FFP) and platelet concentrate (PC) transfusion rate; (b) postoperative chest tube blood loss during the first 24 h after admission to the intensive care unit; (c) mortality during a 6-month follow up observation period; and (d) ventilation time, PaO2/FiO2 - index, and length of stay in the intensive care unit and hospital. From [13] with permission.
Figure 3
Figure 3
Hemotherapy algorithm including point-of-care (POC) techniques. ACT: activated clotting time; ADP: ADPtest; ASPI: ASPItest; A10: amplitude of clot firmness 10 min after clotting time; Cai: ionized calcium; CT: clotting time; EX: EXTEM; FFP: fresh frozen plasma; FIB: FIBTEM; F XIII: factor XIII concentrate; HEP: HEPTEM; ICU: intensive care unit; IN: INTEM; PC: pooled platelet concentrate; PCC: prothrombin complex concentrate; rFVIIa: activated recombinant factor VII; Tc: core temperature; TRAP: TRAPtest. From [13] with permission.
See this image and copyright information in PMC

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