Identification of cystathionine β-synthase inhibitors using a hydrogen sulfide selective probe
- PMID: 23512751
- DOI: 10.1002/anie.201300841
Identification of cystathionine β-synthase inhibitors using a hydrogen sulfide selective probe
Abstract
Buzzing with activity: A hydrogen sulfide selective fluorogenic probe, 7-azido-4-methylcoumarin (AzMC), serves as a highly sensitive assay for cystathionine β-synthase activity, and is suitable for the high-throughput discovery of novel enzyme inhibitors.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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