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. 2013 Aug;15(4):361-71.
doi: 10.1007/s11307-013-0623-1.

Summary report of the First International Workshop on PET/MR imaging, March 19-23, 2012, Tübingen, Germany

Affiliations

Summary report of the First International Workshop on PET/MR imaging, March 19-23, 2012, Tübingen, Germany

Dale L Bailey et al. Mol Imaging Biol. 2013 Aug.

Abstract

We report from the First International Workshop on positron emission tomography/magnetic resonance imaging (PET/MRI) that was organized by the University of Tübingen in March 2012. Approximately 100 imaging experts in MRI, PET and PET/computed tomography (CT), among them early adopters of pre-clinical and clinical PET/MRI technology, gathered from March 19 to 24, 2012 in Tübingen, Germany. The objective of the workshop was to provide a forum for sharing first-hand methodological and clinical know-how and to assess the potential of combined PET/MRI in various applications from pre-clinical research to scientific as well as clinical applications in humans. The workshop was comprised of pro-active sessions including tutorials, specific discussion panels and grand rounds. Pre-selected experts moderated the sessions, and feedback from the subsequent discussions is presented here to a greater readership. Naturally, the summaries provided herein are subjective descriptions of the hopes and challenges of PET/MR imaging as seen by the workshop attendees at a very early point in time of adopting PET/MRI technology and, as such, represent only a snapshot of current approaches.

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Conflict of interest statement

TB is a founder and owner of cmi-experts GmbH, Switzerland. The Department of Preclinical Imaging and Radiopharmacy, University of Tübingen, is the European Preclinical Reference and Trainings Site of Siemens Healthcare. The department has ongoing research collaborations with Siemens and Bruker and licensed patents and inventions related to PET/MRI.

Figures

Fig. 1
Fig. 1
“MindMap” on the clinical role of PET/MRI developed in real time by the participants of the breakout session BS 2 “The role of PET in PET/MRI”.
Fig. 2
Fig. 2
Quantitative parameters in PET, PET/CT and PET/MR.
Fig. 3
Fig. 3
Mandatory corrections and quality control measures in PET only, PET/CT, and PET/MR imaging.
Fig. 4
Fig. 4
Simultaneous quantification of cerebral blood flow ([15O]H2O-PET) and gadolinium bolus T max (perfusion-weighted MRI) in a patient with acute ischemic stroke. Deficits in the right medial cerebral artery territory were found in this case in both modalities. A simultaneous imaging approach allows to cross-evaluate and calibrate new MR techniques of CBF determination in acute stroke against the gold standard [15O]H2O-PET. Data courtesy of the Department of Nuclear Medicine, University of Leipzig (Germany).
Fig. 5
Fig. 5
“MindMap” as presented in the concluding remarks (Dirk Hellwig) illustrating the multiple options of PET, MR, and PET/MRI applications and implications for applications in clinical routine and research.

Comment in

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