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. 1990 Jun:71 ( Pt 6):1355-64.
doi: 10.1099/0022-1317-71-6-1355.

Cloning and molecular characterization of the murine herpesvirus 68 genome

S Efstathiou  1 , Y M Ho, A C Minson
Affiliations

Cloning and molecular characterization of the murine herpesvirus 68 genome

S Efstathiou et al. J Gen Virol. 1990 Jun.

Abstract

Murine herpesvirus 68 (MHV-68) is a naturally occurring herpesvirus of small free-living rodents. In order to facilitate the molecular characterization of the virus genome, a library of cloned restriction fragments has been produced and restriction enzyme cleavage maps deduced for the enzymes BamHI, EcoRI and HindIII. The MHV-68 genome comprises a region of unique DNA of approximately 118 kbp which is flanked by variable numbers of a 1.23 kb repeat unit. The organization of the MHV-68 genome is, therefore, most similar to that of the lymphotropic gamma 2 group of herpesviruses which include herpesvirus saimiri and herpesvirus ateles.

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