Hypothalamic EphA5 facilitates counterregulatory responses: possible role for bidirectional signaling leading to bistability that enhances responsiveness to hypoglycemia
- PMID: 23520275
- PMCID: PMC3609568
- DOI: 10.2337/db12-1735
Hypothalamic EphA5 facilitates counterregulatory responses: possible role for bidirectional signaling leading to bistability that enhances responsiveness to hypoglycemia
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EphA5-EphrinA5 interactions within the ventromedial hypothalamus influence counterregulatory hormone release and local glutamine/glutamate balance during hypoglycemia.Diabetes. 2013 Apr;62(4):1282-8. doi: 10.2337/db12-0982. Epub 2012 Dec 28. Diabetes. 2013. PMID: 23274893 Free PMC article.
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