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. 2013 Mar 22:6:79.
doi: 10.1186/1756-3305-6-79.

Co-infection of tuberculosis and parasitic diseases in humans: a systematic review

Xin-Xu Li  1 , Xiao-Nong Zhou
Affiliations

Co-infection of tuberculosis and parasitic diseases in humans: a systematic review

Xin-Xu Li et al. Parasit Vectors. .

Abstract

Co-infection of tuberculosis and parasitic diseases in humans is an important public problem in co-endemic areas in developing countries. However, there is a paucity of studies on co-infection and even fewer reviews. This review examines 44 appropriate papers by PRISMA from 289 papers searched in PubMed via the NCBI Entrez system (no grey literature) up to December 2012 in order to analyze the factors that influence epidemic and host's immunity of co-infection. The limited evidence in this review indicates that most common parasite species are concurrent with Mycobacterium tuberculosis in multiple organs; socio-demographics such as gender and age, special populations with susceptibility such as renal transplant recipients, patients on maintenance haemodialysis, HIV positive patients and migrants, and living in or coming from co-endemic areas are all likely to have an impact on co-infection. Pulmonary tuberculosis and parasitic diseases were shown to be risk factors for each other. Co-infection may significantly inhibit the host's immune system, increase antibacterial therapy intolerance and be detrimental to the prognosis of the disease; in addition, infection with parasitic diseases can alter the protective immune response to Bacillus Calmette-Guerin vaccination against Mycobacterium tuberculosis.

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Figures

Figure 1
Figure 1
Study selection information regarding co-infection between TB and parasitic diseases.
See this image and copyright information in PMC

References

    1. UNDP, World Bank. WHO Special Programme for Research and Training in Tropical Diseases (TDR): Tropical Disease Research: Progress 1999–2000 . Geneva, Switzerland: World Health Organization Press; 2001. WHO/TDR/GEN/01.5.
    1. World Health Organization. Global tuberculosis control: WHO report 2011. Geneva, Switzerland: World Health Organization Press; 2011. WHO/HTM/TB/2011.16.
    1. World Health Organization. World malaria report: 2010. Geneva, Switzerland: World Health Organization Press; 2010.
    1. World Health Organization. Schistosomiasis: progress report 2001–2011, strategic plan 2012–2020. Geneva, Switzerland: World Health Organization Press; 2013.
    1. World Health Organization. Progress report 2000–2009 and strategic plan 2010–2020 of the global programme to eliminate lymphatic filariasis: halfway towards eliminating lymphatic filariasis. Geneva, Switzerland: World Health Organization Press; 2010. WHO/HTM/NTD/PCT/2010.6.

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