Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013;68(2):219-24.
doi: 10.6061/clinics/2013(02)oa16.

Childhood cancer mortality trends in Brazil, 1979-2008

Sima Ferman  1 , Marceli de Oliveira Santos, Juliana Moreira de Oliveira Ferreira, Rejane de Souza Reis, Julio Fernando Pinto Oliveira, Maria S Pombo-de-Oliveira, Beatriz de Camargo
Affiliations

Childhood cancer mortality trends in Brazil, 1979-2008

Sima Ferman et al. Clinics (Sao Paulo). 2013.

Abstract

Objectives: Childhood cancer mortality has substantially declined worldwide as a result of significant advances in global cancer care. Because limited information is available in Brazil, we analyzed trends in childhood cancer mortality in five Brazilian regions over 29 years.

Methods: Data from children 0-14 years old were extracted from the Health Mortality Information System for 1979 through 2008. Age-adjusted mortality rates, crude mortality rates, and age-specific mortality rates by geographic region of Brazil and for the entire country were analyzed for all cancers and leukemia. Mortality trends were evaluated for all childhood cancers and leukemia using joinpoint regression.

Results: Mortality declined significantly for the entire period (1979-2008) for children with leukemia. Childhood cancer mortality rates declined in the South and Southeast, remained stable in the Middle West, and increased in the North and Northeast. Although the mortality rates did not unilaterally decrease in all regions, the age-adjusted mortality rates were relatively similar among the five Brazilian regions from 2006-2008.

Conclusions: Childhood cancer mortality declined 1.2 to 1.6% per year in the South and Southeast regions.

PubMed Disclaimer

Conflict of interest statement

No potential conflict of interest was reported.

Figures

Figure 1
Figure 1
Trends in age-standardized 0-14 years mortality rates for all childhood cancers and leukemias in Brazil and its 5 different regions.
See this image and copyright information in PMC

References

    1. Chatenoud L, Bertuccio P, Bosetti C, Levi F, Negri E, La Vecchia C. Childhood cancer mortality in America, Asia, and Oceania, 1970 through 2007. Cancer. 2010;116(21):5063–74. - PubMed
    1. Bosetti C, Bertuccio P, Chatenoud L, Negri E, Levi F, La Vecchia C. Childhood cancer mortality in Europe, 1970-2007. Eur J Cancer. 2010;46(2):384–94. - PubMed
    1. La Vecchia C, Levi F, Lucchini F, Lagiou P, Trichopoulos D, Negri E. Trends in childhood cancer mortality as indicators of the quality of medical care in the developed world. Cancer. 1998;83(10):2223–7. - PubMed
    1. Levi F, La Vecchia C, Negri E, Lucchini F. Childhood cancer mortality in Europe, 1955-1995. Eur J Cancer. 2001;37(6):785–809. - PubMed
    1. Ribeiro KB, Lopes LF, De Camargo B. Trends in childhood leukemia mortality in Brazil and correlation with social inequalities. Cancer. 2007;110(8):1823–31. - PubMed

LinkOut - more resources