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. 2012;14(3-4):48-55.

Nocturia: focus on etiology and consequences

Jeffrey P Weiss  1
Affiliations

Nocturia: focus on etiology and consequences

Jeffrey P Weiss. Rev Urol. 2012.

Abstract

Nocturia is a condition characterized by the need to awaken ≥ 1 times per night to void. Although nocturia is a multifactorial condition that can coexist with other lower urinary tract symptoms, the most common causal factor is nighttime overproduction of urine. Many people with nocturia do not seek help, accepting it as a natural consequence of aging. However, nocturia is common in men and women of all ages and has a profound impact on quality of life, especially in the young, that may be associated with increased morbidity and mortality. Nocturia as a condition deserves public health attention.

Keywords: Nighttime urine overproduction; Nocturia; Quality of life; Sleep disruption.

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Figures

Figure 1
Figure 1
Prevalence of nocturia in men (A) and women (B) from a meta-analysis of epidemiology studies, by number of nocturia episodes per night. Reproduced with permission from Bosch JL, Weiss JP.
Figure 2
Figure 2
Mechanism of nocturnal overproduction of urine. AQP, aquaporin; ATP, adenosine triphosphate; AVP, arginine vasopressin; cAMP, cyclic adenosine monophosphate; GTP, guanosine triphosphate; PKA, protein kinase A. A portion of this image appears courtesy of Joseph Verbalis, MD, Georgetown University Medical Center, Washington, DC.
Figure 3
Figure 3
Example of a frequency volume chart.
See this image and copyright information in PMC

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