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Case Reports
. 2013 Mar 25:2013:bcr2013008637.
doi: 10.1136/bcr-2013-008637.

Small colony variant-producing S aureus prosthesis joint infection highlighted by sonication and treated with prolonged high doses of daptomycin

Camille Piffaut  1 , Sébastien Lustig, Frédéric Laurent, Christian Chidiac, Tristan Ferry; Lyon BJI Study Group
Collaborators, Affiliations
Case Reports

Small colony variant-producing S aureus prosthesis joint infection highlighted by sonication and treated with prolonged high doses of daptomycin

Camille Piffaut et al. BMJ Case Rep. .
No abstract available

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Figures

Figure 1
Figure 1
Periprosthetic pathological lucencies (A, arrows), associated with MSSA SCV in cultures (small colonies) obtained with sonication from prosthesis explantation (B, arrows). After reimplantation and a total of 3 months of antimicrobial therapy, no relapse occurred at 1 year (C, x-ray).
See this image and copyright information in PMC

References

    1. Trampuz A, Piper KE, Jacobson MJ, et al. Sonication of removed hip and knee prostheses for diagnosis of infection. N Engl J Med 2007;357:654–63 - PubMed
    1. Proctor RA, Von Eiff C, Kahl BC, et al. Small colony variants: a pathogenic form of bacteria that facilitates persistent and recurrent infections. Nat Rev Microbiol 2006;4:295–305 - PubMed
    1. Osmon DR, Berbari EF, Berendt AR, et al. Diagnosis and management of prosthetic joint infection: clinical practice guidelines by the infectious diseases society of America. Clin Infect Dis 2013;56:e1–25 - PubMed

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