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. 2013:2013:715380.
doi: 10.1155/2013/715380. Epub 2013 Feb 26.

Stroke care in young patients

L Tancredi  1 , F Martinelli Boneschi, M Braga, I Santilli, C Scaccabarozzi, P Lattuada, M Sessa, L Fumagalli, S Iurlaro, I Neromante, M L De Lodovici, D V Roccatagliata, G Giacalone, M Arnaboldi, V Crespi, E Agostoni, G C Comi, C Ferrarese, R Sterzi
Affiliations

Stroke care in young patients

L Tancredi et al. Stroke Res Treat. 2013.

Abstract

The aims of this study were (i) to evaluate the clinical features of a consecutive series of young patients with ischemic stroke and (ii) to assess the changes in the clinical management of these patients over the study period. All consecutive cases of young adults aged 16 to 44 years, with ischemic stroke, that were admitted between 2000 and 2005 in 10 Italian hospitals were included. We retrospectively identified 324 patients. One or more vascular risk factors were present in 71.5% of the patients. With respect to the diagnostic process, an increase in the frequency of cerebral noninvasive angiographic studies and a decrease in the use of digital subtraction angiography were observed (P < 0.001 and P = 0.03, resp.). Undetermined causes decreased over 5-year period of study (P < 0.001). The diagnosis of cardioembolism increased. Thrombolysis was performed for 7.7% of the patients. PFO closure (8%) was the most frequently employed surgical procedure. In conclusion, the clinical care that is given to young patients with ischemic stroke changed over the study period. In particular, we detected an evolution in the diagnostic process and a reduction in the number of undetermined cases.

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Figures

Figure 1
Figure 1
Changes over time (2000–2005) of the frequency of angiographic studies.
Figure 2
Figure 2
TOAST criteria stratified by age classes.
Figure 3
Figure 3
: TOAST classification: changes over time (2000–2005) of undetermined and cardioembolic strokes.
See this image and copyright information in PMC

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