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Review
. 2013 Apr;44(2):137-51.
doi: 10.1016/j.ocl.2013.01.001. Epub 2013 Feb 21.

Bisphosphonate therapy and atypical fractures

Anas Saleh  1 , Vishal V Hegde, Anish G Potty, Joseph M Lane
Affiliations
Review

Bisphosphonate therapy and atypical fractures

Anas Saleh et al. Orthop Clin North Am. 2013 Apr.

Abstract

Atypical femoral fractures have attracted a great deal of attention and controversy in the osteoporosis community because of their association with prolonged bisphosphonate therapy. The purpose of this article is to review the epidemiologic evidence linking bisphosphonates to atypical fractures and to highlight the potential pathologic mechanisms involved in such fractures. A management plan is provided based on the available evidence.

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