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Review
. 2013 Apr;80(4):225-33.
doi: 10.3949/ccjm.80a.12182.

Carbapenem-resistant Enterobacteriaceae: a menace to our most vulnerable patients

Federico Perez  1 , David Van Duin
Affiliations
Review

Carbapenem-resistant Enterobacteriaceae: a menace to our most vulnerable patients

Federico Perez et al. Cleve Clin J Med. 2013 Apr.

Abstract

The emergence of carbapenem-resistant Enterobacteriaceae (CRE) highlights the importance of effective antibiotics to maintain the safety of our health care system. Clinicians will encounter CRE as a cause of difficult-to-treat and often fatal infections in hospitalized patients. We review the mechanisms of carbapenem resistance, the dissemination and clinical impact of these resistant organisms, and challenges to their detection, treatment, and control.

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