The lab without walls: a deployable approach to tropical infectious diseases
- PMID: 23553225
- PMCID: PMC3617842
- DOI: 10.4269/ajtmh.12-0704
The lab without walls: a deployable approach to tropical infectious diseases
Abstract
The Laboratory Without Walls is a modular field application of molecular biology that provides clinical laboratory support in resource-limited, remote locations. The current repertoire arose from early attempts to deliver clinical pathology and public health investigative services in remote parts of tropical Australia, to address the shortcomings of conventional methods when faced with emerging infectious diseases. Advances in equipment platforms and reagent chemistry have enabling rapid progress, but also ensure the Laboratory Without Walls is subject to continual improvement. Although new molecular biology methods may lead to more easily deployable clinical laboratory capability, logistic and technical governance issues continue to act as important constraints on wider implementation.
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References
-
- Inglis TJ, Garrow SC, Adams C, Henderson M, Mayo M. Dry-season outbreak of melioidosis in Western Australia. Lancet. 1998;352:1600. - PubMed
-
- Inglis TJ, Levy A, Merritt AJ, Hodge M, McDonald R, Woods DE. Melioidosis risk in a tropical industrial environment. Am J Trop Med Hyg. 2009;80:78–84. - PubMed
-
- Inglis TJ, Merritt A, Jayasinghe I, Montgomery J, Thevanesam V. Logistic aspects of a deployable molecular microbiology laboratory. J Mil Vet Health. 2008;17:6–10.
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