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Randomized Controlled Trial
. 2013 Jul;17(6):2031-44.
doi: 10.1007/s10461-013-0469-1.

Feasibility, acceptability and preliminary efficacy of an online peer-to-peer social support ART adherence intervention

Keith J Horvath  1 , J Michael Oakes, B R Simon Rosser, Gene Danilenko, Heather Vezina, K Rivet Amico, Mark L Williams, Jane Simoni
Affiliations
Randomized Controlled Trial

Feasibility, acceptability and preliminary efficacy of an online peer-to-peer social support ART adherence intervention

Keith J Horvath et al. AIDS Behav. 2013 Jul.

Abstract

This study describes the results of an online social support intervention, called "Thrive with Me" (TWM), to improve antiretroviral therapy (ART) adherence. HIV-positive gay or bisexually-identified men self-reporting imperfect ART adherence in the past month were randomized to receive usual care (n = 57) or the eight-week TWM intervention (n = 67). Self-reported ART outcome measures (0-100 % in the past month) were collected at baseline, post-intervention, and 1-month follow-up. Follow-up assessment completion rate was 90%. Participants rated (1-7 scale) the intervention high in information and system quality and overall satisfaction (Means ≥ 5.0). The intervention showed modest effects for the overall sample. However, among current drug-using participants, the TWM (vs. Control) group reported significantly higher overall ART adherence (90.1 vs. 57.5% at follow-up; difference = 31.1, p = 0.02) and ART taken correctly with food (81.6 vs. 55.7% at follow-up; difference = 47.9, p = 0.01). The TWM intervention appeared feasible to implement, acceptable to users, and demonstrated greatest benefits for current drug users.

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Figures

Figure 1
Figure 1
Participant flow in the Thrive with Me study.
Figure 2
Figure 2. Thrive with Me
Intervention Home Page.
Figure 3
Figure 3. Thrive with Me
Intervention “My Meds” Page.
Figure 4
Figure 4. Thrive with Me
Intervention “My Content” Page.
Figure 5
Figure 5
Pre-to-post Change in Percent ART Adherence for the TWM Intervention and Null Control Arm Participants.
See this image and copyright information in PMC

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