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Case Reports
. 2013 Jun;51(6):2006-7.
doi: 10.1128/JCM.00446-13. Epub 2013 Apr 3.

Identification of an influenza A H1N1/2009 virus with mutations in the matrix gene causing a negative result by a commercial molecular assay

Case Reports

Identification of an influenza A H1N1/2009 virus with mutations in the matrix gene causing a negative result by a commercial molecular assay

Matthew J Binnicker et al. J Clin Microbiol. 2013 Jun.
No abstract available

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Figures

Fig 1
Fig 1
Analysis of an influenza A virus 2009/H1N1 strain with point mutations in the matrix gene by real-time PCR (A) and agarose gel electrophoresis (B). The positive control (line and lane 1), patient culture isolate (lines and lanes 2 and 3), and negative control (line and lane 4) were tested by the Prodesse ProFlu+ real-time PCR assay. The PCR product was analyzed in real time for fluorescent output (A) and by agarose gel electrophoresis with ethidium bromide staining (B). Lanes L, molecular weight ladders.

References

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    1. Zheng X, Todd KM, Yen-Lieberman B, Kaul K, Mangold K, Shulman ST. 2010. Unique finding of a 2009 H1N1 influenza virus-positive clinical sample suggests matrix gene sequence variation. J. Clin. Microbiol. 48:665–666 - PMC - PubMed
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