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Comment
. 2013;11(3):e1001509.
doi: 10.1371/journal.pbio.1001509. Epub 2013 Mar 12.

Positive charges put the brakes on ribosomes

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Comment

Positive charges put the brakes on ribosomes

Roland G Roberts. PLoS Biol. 2013.
No abstract available

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Conflict of interest statement

The author has declared that no competing interests exist.

Figures

Figure 1
Figure 1. What slows ribosomes down? The freely translating ribosome (A) was thought to be slowed by codons that need rare tRNAs (B) or by mRNA secondary structure (C). Charneski and Hurst, however, show that the dominant braking factor is the presence of positively charged amino acids (red beads) in the exit tunnel (D).

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