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. 2011 Jan;25(1):71-3.
doi: 10.1016/S1674-8301(11)60009-2.

Successful conservative management with methotrexate and mifepristone of cervical pregnancy

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Successful conservative management with methotrexate and mifepristone of cervical pregnancy

Eliza Shrestha et al. J Biomed Res. 2011 Jan.

Abstract

This study investigated possible effective treatments for cervical pregnancy, a rare form of ectopic pregnancy. The clinical records of 11 cases of ectopic pregnancy admitted to the Third Affiliated Hospital of Sun Yat-sen University from 1998 to 2010 were analyzed. All patients were treated with intermuscular injection of methotrexate (MTX, 50 mg), and oral mifepristone (25 mg, bid). All cases were successfully cured by conservative treatments using methotrexate plus mifepristone. Cervical pregnancy is a contributive factor to mutiple abortions and curettages. Methotrexate plus mifepristone, curettage through hysteroscopy and intracervical obturation with gauze are effective treatments of cervical pregnancy without the need for surgical intervention.

Keywords: cervical pregnancy; conservative treatment; ectopic pregnancy.

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Conflict of interest statement

The authors reported no conflict of interests.

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