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. 2013 Apr 4:13:297.
doi: 10.1186/1471-2458-13-297.

Spatial-temporal variations of Schistosoma japonicum distribution after an integrated national control strategy: a cohort in a marshland area of China

Yi-Biao Zhou  1 , Song Liang, Geng-Xin Chen, Chris Rea, Shi-Min Han, Zong-Gui He, Yuan-Pei Li, Jian-Guo Wei, Gen-Ming Zhao, Qing-Wu Jiang
Affiliations

Spatial-temporal variations of Schistosoma japonicum distribution after an integrated national control strategy: a cohort in a marshland area of China

Yi-Biao Zhou et al. BMC Public Health. .

Abstract

Background: Schistosomiasis transmission is typically focal. Understanding spatial variations of Schistosoma infections and their associated factors is important to help to invent site-specific intervention strategies.

Methods: A five-year longitudinal study was carried out prospectively in 12 natural villages, Guichi district of Anhui province. A GIS-based spatial analysis was conducted to identify geographic distribution patterns of schistosomiasis infections at the household scale.

Results: The results of the spatial autocorrelation analysis for 2005 showed that there were significant spatial clusters of human infections at the household level, and these results were in agreement with that of the spatial scan statistic. As prevalence of infections in humans decreased over the course of control, the spatial distribution of these infections became less heterogeneous.

Conclusions: The findings imply that it may be necessary to re-assess risk factors of S. japonicum transmission over the course of control and to adjust accordingly control measures in the communities.

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Figures

Figure 1
Figure 1
The study location in the Qiupu River region in Guichi district, Anhui province, People’s Republic of China.
Figure 2
Figure 2
Global spatial autocorrelation analyses for annual prevalence/incidence of infection S. japonicum from 2005 to 2009. Prevalence/Incidence represents that of the cohort population. The first point (2005) in Prevalence/Incidence represents infection prevalence of the cohort, and the remaining points represent infection incidence of the cohort. The points in Household (Moran’s I) represent the Moran’s I values at household level.
Figure 3
Figure 3
LISA Moran scatter plot for S. japonicum infection prevalence at the household level: (a) 2005, (b) 2007, (c) 2009.
Figure 4
Figure 4
Spatial cluster location of S. japonicum transmission at the household level in 2005 year. Black dots represent the households. Rate Ratio is presented in the parenthesis.
See this image and copyright information in PMC

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