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. 2013 Apr;19(4):413-5.
doi: 10.1038/nm.3147.

Heart repair by cardiac reprogramming

Affiliations

Heart repair by cardiac reprogramming

Young-Jae Nam et al. Nat Med. 2013 Apr.
No abstract available

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Conflict of interest statement

COMPETING FINANCIAL INTERESTS

The authors declare no competing financial interests.

Competing financial interests

Declaration: R.T.L. is a founder of and consultant to Provasculon. C.L.M. is a founder of and consultant to Pluriomics.

Figures

Figure 1
Figure 1
Heart repair by in vivo reprogramming of nonmyocytes into iCLMs. After myocardial infarction, a viral cocktail of cardiac transcription factors or miRNAs is directly injected into the border zone adjacent to the infarcted myocardium. The forced expression of reprogramming factors in the heart after myocardial infarction generates iCLMs in situ and leads to the improvement of contractile function and reduction of scar formation. LV, left ventricle.

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