Overcoming the problem of pseudohypoxemia in myeloproliferative disorders: Another trick in the bag
- PMID: 23559729
- PMCID: PMC3610454
- DOI: 10.4103/0972-5229.106504
Overcoming the problem of pseudohypoxemia in myeloproliferative disorders: Another trick in the bag
Abstract
Pseudohypoxaemia or spurious hypoxaemia is a recurrent problem faced on arterial blood gas analysis in patients with hyperleucocytosis leading to management dilemmas and unnecessary respiratory interventions. Various methods have been suggested to reduce the magnitude of this problem. We report a case of pseudohypoxaemia due to blast crisis in a patient of chronic myeloid leukaemia where arterial blood gas analysed from precooled syringe helped us resolve the problem and hastened our weaning from oxygen therapy.
Keywords: Chronic myeloid leukaemia; precooling; pseudohypoxaemia.
Conflict of interest statement
References
-
- Fox M, Brody J, Weintraub W. Leukocyte larceny: A cause of spurious hypoxemia. Am J Med. 1979;67:742–6. - PubMed
-
- Chishiro T, Suzuki K, Matsuo N. Metabolism of the circulating leukocyte. Physiol Rev. 1965;45:674–720. - PubMed
-
- Hess CE, Nichols AB, Hunt WB, Suratt PM. Pseudohypoxemia secondary to leukemia and thrombocytosis. N Eng J Med. 1979;301:361–3. - PubMed
-
- Charan NB, Marks M, Carvalho P. Use of plasma for arterial blood gas analysis in leukemia. Chest. 1994;105:954–5. - PubMed
-
- Khoo SM, Lee KH, Notley M. Spurious hypoxaemia in a patient with leukaemia and extreme leucocytosis. Singapore Med J. 2003;44:208–10. - PubMed
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