Eccrine angiomatous hamartoma, with verrocous hemangioma-like features: A case report

Abstract

Eccrine angiomatous hamartoma (EAH) is a rare, benign cutaneous tumor. It is characterized by the proliferation of the eccrine gland elements that are closely associated with capillary proliferation. Patients usually present with a solitary nodule on the extremities that appeared at birth or during the prepubertal years. We report a rare case of EAH in a 13-year-old boy, with clinical features suggesting melanoma. Histologically, an EAH with changes resembling a verrucous hemangioma was noted.

Keywords: angiomatous hamartoma; eccrine glands; verrucous.

Fig. (1)

Hyperkeratosis, papillomatosis, and blood vessel proliferation in the superficial dermis (H&E, ×200).

Fig. (2A)

The deep dermis and subcutaneous fat reveals eccrine structures proliferation intermingled with vascular channels (H&E, ×100).

Fig. (2B)

Pan-cytokeratin immunostaining highlights the eccrine glands and ducts (Pan-cytokeratin, PAP immunohistochemistry, ×100).

Fig. (2C)

CD31 immunostaining highlights the vascular structure (CD31, PAP immunohistochemistry, ×100).